PROGRAM SCHEDULE
The program is organized in eight sessions that are chaired by speakers who are leaders in their respective fields. Each session includes talks by speakers that are 25 minute talk plus 5 minutes questions or 15min talk plus 5min questions, and short oral presentations that are 10 minute talk plus 2 minutes questions. Short oral presentations are selected from submitted abstracts. Posters are viewed for the duration of the conference.
To download the program schedule please click here
| May 29 Wednesday | Day 1 | Arrival | |
| 15:00-18:00 | Registration | ||
| 19:00 | Welcome Dinner | ||
| May 30 Thursday | Day 2 | ||
| 7:00-8:15 | Breakfast | ||
| 8:30-11:00 | Session 1: Systems Immunology of Infections | ||
| Chair: Anne O’Garra | |||
| 8:30-9:00 | Tom Ottenhoff, Leiden University Medical Center, The Netherlands | Non-classical innate and adaptive immunity in host defence against Mycobacterium tuberculosis in humans | |
| 9:00-9:30 | Adrian Hayday, The Francis Crick Institute, UK | Epithelial regulation and dysregulation of human adaptate T cells | |
| 9:30-9:50 | Shai Shen-Orr, Technion-Israel Institute of Technology, Israel | Charting the Immunological Landscape – System Dynamics and Clinical Implications | |
| 9:50-10:10 | Michelle Linterman, Babraham Institute, UK | The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCR clonotypes | |
| 10:10-11:00 | Jorge Domínguez-Andrés, Radboud UMC, The Netherlands | The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity | |
| Simone Moorlag, Radboud UMC, The Netherlands | BCG-vaccination induces innate memory in human neutrophils leading to nonspecific protection against reinfection | ||
| Wivine Burny, GSK Vaccine, Belgium | Transcriptomics analysis of early responses to HBs vaccines containing an Adjuvant System in humans | ||
| Jayanti Mania-Pramanik, ICMR-National Institute for Research in Reproductive Health, India | Contribution of host immunogenetic factors towards risk of HIV transmission: A study in Indian cohorts | ||
| 11:00-11:30 | Coffee break & Poster viewing | ||
| 11:30-13:45 | Session 2: Discovering and Translating Human T cell Immunity | ||
| Chair: Peter Katsikis | |||
| 11:30-12:00 | Rene van Lier, Sanquin, The Netherlands | Leaving home: A role for TRM in Systemic Immunity? | |
| 12:00-12:30 | Peter Katsikis, Erasmus University Medical Center, The Netherlands | miRNA as regulators of CTL immunity | |
| 12:30-13:45 | Sascha Rutz, Cancer Immunology, Genentech, South San Francisco, United States of America | Gene editing in primary human T cells using CRISPR/Cas9 | |
| Agnese Losurdo, Humanitas Research Hospital, Italy | Defining T cell dysfunctionality in breast cancer by single cell analysis: implications for immunotherapy | ||
| Manzhi Zhao, Erasmus University Medical Center, The Netherlands | Establishment of an in vitro CD8 T cell exhaustion model | ||
| Etienne Masle-Farquhar, Garvan Institute of Medical Research, Australia | The effects of Germline STAT3-activating mutations from autoimmunity and lymphoid malignancy on mouse and human T cell development and function | ||
| Lisanne Lutter, University Medical Centre Utrecht, The Netherlands | Characterization of regulatory T cell programming and heterogeneity in an autoimmune inflammatory environment | ||
| Emmanuelle Godefroy, CRCINA, INSERM U1232, France | A novel gut-derived microbiota-specific circulating CD4+/CD8a+ human Treg subset: potential roles in homeostasis and diseases | ||
| 13:45 | Lunch | ||
| 18:30-19:30 | Poster viewing & Drinks | ||
| 19:30 | Dinner | ||
| May 31 Friday | Day 3 | ||
| 7:00-8:15 | Breakfast | ||
| 8:30-11:06 | Session 3: Discovering and Translating Human T cell Immunity | ||
| Chair: Federica Sallusto | |||
| 8:30-9:20 | Mark Davis, Stanford University, USA | Tools for T cells: Specificity and function in autoimmunity, infectious diseases and cancer | |
| 9:20-9:50 | Federica Sallusto, Università della Svizzera Italiana, Switzerland | Human Memory T Cell Subsets: From Phenotype To Function | |
| 9:50-10:10 | Rama Amara Rao, Emory University, USA | PD-1 Blockade Combined with Therapeutic Vaccination for Functional Cure Against HIV/AIDS | |
| 10:10-10:30 | Amit Awasthi, Translational Health Science and Technology Institute, India | EGFR-HIF1a signalling axis positively regulates the development of Th9 cells | |
| 10:30-11:06 | Eloise Scamardella, Humanitas Research Hospital, Italy | Interferon regulatory factor (IRF8) regulates memory formation by restraining FOXO1 expression | |
| Steven Koetzier, Erasmus University Medical Center, The Netherlands | Deciphering glucocorticoid-resistant T helper cells driving multiple sclerosis disease activity | ||
| Julia Bier, Immunology, Garvan Institute, Sydney, Australia | Activated PI3K Delta Syndrome: dissecting the effects of PI3K hyperactivation over T helper differentiation and function | ||
| 11:06-11:30 | Coffee break & Poster viewing | ||
| 11:30-13:45 | Session 4: Understanding and Translating Human B cell responses | ||
| Chair: Rene Toes | |||
| 11:30-12:00 | Antonio Lanzavecchia, Università della Svizzera Italiana, Switzerland | Lessons from the analysis of the immune response to P. falciparum: the power of clonal selection | |
| 12:00-12:30 | Xiao-Ning Xu, Imperial College London, UK | Dissection of antibody responses to emerging infections in humans by yeast display | |
| 12:30-13:00 | Rene Toes, Leiden University Medical Center, The Netherlands | Take the bitter with the sweet; on the role of variable domain glycans and the breach of tolerance of auto-reactive B-cells in Rheumatoid Arthritis | |
| 13:00-13:20 | Joshy Jacob, Emory University, USA | Templated mutagenesis and the origin of B cell somatic mutants | |
| 13:20-13:45 | Joanne H Reed, Garvan Institute of Medical Research, Australia | Evolution of Pathogenic Autoantibody by Lymphoma Mutations in Rogue B Cell Clones | |
| Ian Setliff, Vanderbilt University Medical Center, USA | High-throughput mapping of B-cell receptor sequence to antigen specificity | ||
| 13:45 | Lunch | ||
| 18:30-19:30 | Poster viewing & Drinks | ||
| 19:30 | Dinner | ||
| June 1 Saturday | Day 4 | ||
| 7:00-8:15 | Breakfast | ||
| 8:30-11:05 | Session 5: Tumor Immunotherapy | ||
| Chair: Stephen Schoenberger | |||
| 8:30-9:00 | Ugur Sahin, BioNTech Pharmaceuticals, Germany | RNA-based vaccine approaches | |
| 9:00-9:30 | Stephen Schoenberger, La Jolla Institute for Allergy & Immunology, USA | Functional identification of tumor NeoAg | |
| 9:30-10:00 | Özlem Türeci, Cluster for Individualized ImmunoIntervention (CI3), Germany | Novel immunotherapies based on targeting Claudin family members | |
| 10:00-10:20 | George Pavlakis, National Cancer Institute, USA | Clinical development of heterodimeric IL-15 for cancer immunotherapy | |
| 10:20-10:40 | Enrico Lugli, Humanitas Clinical and Research Center, Italy | High-Dimensional Single-Cell Profiling Identifies an Effector Treg Molecular Program Governing Human Lung Cancer Disease Progression | |
| 10:40-11:05 | Zhizhang Yang, Mayo Clinic, USA | Mass cytometry defines loss of costimulatory receptor expression as a novel immune signature in follicular lymphoma | |
| Thomas Duhen, Providence Cancer Institute, USA | A new strategy to identify and expand tumor-reactive CD8 TILs in human solid tumors | ||
| 11:05-11:30 | Coffee break & Poster viewing | ||
| 11:30-13:10 | Session 6: Systems Immunology and Vaccines | ||
| Chair: Bali Pulendran | |||
| 11:30-12:00 | Bali Pulendran, Stanford University, USA | System-biological approaches to define immunological mechanisms of vaccine-induced immunity | |
| 12:00-12:30 | Ken Ishii, University of Tokyo, Japan | Nuclear cytokines and extracellular nucleic acids in infection and vaccination | |
| 12:30-12:50 | Ioanna Skountzou, Emory University, USA | TIV immunization with a thermostable microneedle patch-Immunogenicity and Transcriptomics results from a Phase I Clinical Trial | |
| 12:50-13:10 | Petter Brodin, Karolinska Institute, Sweden | Systems-level analysis of immune variation and the influence of environmental exposures early in life | |
| 13:10 | Lunch | ||
| 17:30 | Tour of Asklepeion | ||
| 19:30 | Dinner Restaurant Oromedon | ||
| June 2 Sunday | Day 5 | ||
| 7:00-8:15 | Breakfast | ||
| 8:30-11:00 | Session 7: Discovering and Translating Innate Immunity | ||
| Chair: Roxane Tussiwand | |||
| 8:30-9:00 | Mihai Netea, Radboud University Medical Center, The Netherlands | Metabolic and Epigenetic Reprogramming in trained Immunity | |
| 9:00-9:30 | Anne O’Garra, The Francis Crick Institute, UK | Cytokine interference in immunity to infection | |
| 9:30-10:00 | Roxane Tussiwand, University of Basel, Switzerland & NIH, USA | When origin matters: redefining the plasmacytoid dendritic cell subset | |
| 10:00-10:20 | Eynav Klechevsky, Washington University in St. Louis, USA | Upstream regulation of autoimmunity and cancer via human dendritic cell subsets | |
| 10:20-10:40 | Evangelos Andreakos, Biomedical Research Foundation, Academy of Athens, Greece | Lambda interferons constitute dual function cytokines mediating antiviral immunity and damage control | |
| 10:40-11:00 | Dina Alexandropoulos, Icahn School of Medicine at Mount Sinai, USA | Immune Profiling and Target Identification of Human Liver Inflammatory Diseases | |
| 11:00-11:30 | Coffee break & Poster viewing | ||
| 11:30-13:50 | Session 8: Translating immunity: From Bedside to Bench and Back | ||
| Chair: Helen Su | |||
| 11:30-12:20 | Anahita Fathi, University Medical Center Hamburg-Eppendorf, Germany | First-in-human clinical phase I trial of a novel virally vectored vaccine candidate against MERS-CoV | |
| Adriana Tomic, Stanford University, USA | SIMON, an automated machine learning system reveals immune signatures of influenza vaccine responses | ||
| Rosa Barreira da Silva, Genentech, USA | Monocyte homeostasis is coordinated by N-terminal cyclization of CCR2 ligands | ||
| Shyam Sushama Jose, St. Anne’s University Hospital, BRNO, Czech Republic | Non-telomeric function of telomerase complex regulates pattern recognition receptors downstream signaling in tissue organoid models | ||
| 12:20-12:50 | Yong-Jun Liu, Sanofi, France | Translating human immunobiology to medicine | |
| 12:50-13:20 | Helen Su, National Institutes of Health (NIH), USA | Mechanistic insights into human immunity through the study of a novel human immunodeficiency-immunodysregulation disorder | |
| 13:20-13:50 | Rino Rappuoli, GSK Vaccines, Italy | Antimicrobial resistance, a threat for our planet as big as climate change, and the role of vaccines | |
| 13:50 | Lunch | ||
| 20:00 | Gala dinner | ||
| June 3 Monday | Day 6 | Departure | |
| 7:00-9:30 | Breakfast |