PROGRAM SCHEDULE
PROGRAM SCHEDULE
A program schedule outline is presented below. Program will be updated with topics and speakers at a later time point.
| Speakers | Session | |
| October 23 Monday | Day 1 | Arrival |
| 15:00-18:00 | Registration | |
| 19:00 | Welcome Dinner | |
| October 24 Tuesday | Day 2 | |
| 7:00-8:15 | Breakfast | |
| 8:30-11:00 | Session 1: SARS-CoV-2 | |
| Chair: Jamie Wilson | ||
| 8:30-8:55 | Danny Altmann | Long Covid – immunopathology, challenges, policy |
| 8:55-9:20 | Irina Lehmann | SARS-COV-2 infectivity in nasal tissues |
| 9:20-9:45 | Clare Lloyd | Stromal-Immune Interactions Regulating Pulmonary Immunity |
| 9:45-10:10 | Antonio Lanzavecchia | Correlates of protection: neutralization versus effector function |
| 10:10-11:00 | Short Talks | |
| Antonella Prisco | Agent-based modeling of the immune response to an adenoviral covid-19 vaccine | |
| Daryl Geers | The prolonged effect of COVID-19 priming vaccination on the immunogenicity of bivalent boosters | |
| Mengyun Hu | Systems Vaccinology of the Sars-Cov-2 mRNA Vaccine in Lung Transplant Patients | |
| Qiyi Zhao | Estrogen Receptor Alpha Inhibits Immunogenic Cell Death by Suppressing HMGB1 Sumoylation | |
| 11:00-11:30 | Coffee break & Poster viewing | |
| 11:30-13:45 | Session 2: Discovering and Translating Human T cell Immunity | |
| Chair: Yvonne Bordon | ||
| 11:30-11:55 | Helen Su | New insights into mechanisms of human immunity from studying a novel inborn error of immunity |
| 11:55-12:20 | Federica Sallusto | Human T Lymphocytes: Differentiation and Immune Regulation |
| 12:20-12:45 | Stuart Berzins | A three-stage developmental pathway for human Vγ9Vδ2 T cells within the postnatal thymus |
| 12:45-13:10 | Amit Awasthi | Gut microbiota metabolite succinate promotes intestinal inflammation |
| 13:10-13:45 | Short Talks | |
| Honghong Sun | TIPE proteins control directed migration of human T cells by directing GPCR and lipid second messenger signaling | |
| Emmanuelle Godefroy | Human Microbiota-Reactive DP8α Regulatory T Cells In Health and Gut-related Disorders | |
| Julija Djordjevic | Colorectal cancer-associated bacteria expand CD4- CD8- T cells endowed with anti-tumor properties | |
| 13:45 | Lunch | |
| 18:30-19:30 | Poster viewing | |
| 19:30 | Dinner | |
| October 25 Wednesday | Day 3 | |
| 7:00-8:15 | Breakfast | |
| 8:30-11:00 | Session 3: Systems Immunology | |
| Chair: Bali Pulendran | ||
| 8:30-8:55 | Petter Brodin | Immunomodulatory functions of testosterone in humans |
| 8:55-9:20 | Jenny Jiang | High-throughput and high-dimensional profiling of antigen-specific T cells |
| 9:20-9:45 | Eynav Klechevsky | Immune Regulation and Dysregulation mediated by Human Dendritic Cell Subsets |
| 9:45-10:10 | Bali Pulendran | Integrated Organ Immunity |
| 10:10-10:35 | Rafick Sékaly | Metabolic regulation of Viral infections |
| 10:35-11:00 | Short Talks | |
| Monika Rottstegge | Human miRNome and transcriptome profiling identifies a dose-dependent signature induced by the Ebola vaccine rVSV-ZEBOV | |
| Cheryl Day | Transcriptional changes in monocytes and NK cells in HIV-exposed uninfected infants are transient and not driven by epigenetic reprogramming | |
| 11:00-11:30 | Coffee break & Poster viewing | |
| 11:30-13:45 | Session 4: Infectious diseases | |
| Chair: Stephen Schoenberger | ||
| 11:30-11:55 | George Gao | TBA |
| 11:55-12:20 | Anne O’Garra | Cytokines: Orchestrating immune responses in lung disease with a focus on tuberculosis: How transcriptomics can lead the way |
| 12:20-12:45 | Jyothi Rengarajan | Systems-level analysis reveals impaired alveolar macrophage responses to Mycobacterium tuberculosis in persons living with HIV |
| 12:45-13:10 | Ian F. Hermans | mRNA vaccine against malaria tailored for liver-resident memory T cells |
| 13:10-13:45 | Short Talks | |
| Luiz Gardinassi | Integrated multicohort analysis identifies conserved transcriptional signatures of clinical malaria | |
| Francesca Mancini | Moving from preclinical to clinical testing: a GMMA-based vaccine candidate to fight shigellosis | |
| Linda Djune Yemeli | Ivermectin treatment of loiasis: A balance between the pro/anti-inflammatory cytokines account for the absence of treatment related adverse events | |
| 13:45 | Lunch | |
| 17:00-18:30 | Short Talks | |
| Jielong Zhou | Microwave Ablation Shock Transforms ‘Cold’ Osteosarcoma into ‘Hot’ One Through Inflammatory Reconstitution | |
| Gabriele Inchingolo | Harnessing T memory stem cells for adoptive immunotherapy of cancer | |
| Ling Li | Bryostatin expands and improves the function of exhausted T cells by upregulating MAP Kinase 11 | |
| Gwenann Cadiou | Impact of PD-1 or TIGIT genetic deletion on the functions of melanoma-specific T lymphocytes | |
| Thomas Duhen | Lineage tracing reveals heterogeneity within tumor-reactive CD8 T cells in mismatch repair-proficient (MMR-p) CRC | |
| Kou Hioki | A combination of TLR9 and STING agonists induces potent neopeptide-specific T cell immunity and provides anti-tumor protection in murine tumor models | |
| Audrey Merienne | Search for neoepitope-specific CD8 T cells generated in a TAP1-deficient context in colorectal cancers | |
| Christopher Schliehe | CUG-initiated cryptic peptide translation up and downstream of canonical AUG start codons is enhanced by Pam3CSK4 and induces tumor regression in mice | |
| Amelie Guiho | A new antigen identification strategy for cancer immunotherapy: peptides derived from long non-coding RNA | |
| 18:30-19:00 | Meet the editors: Tips on scientific publishing | |
| 19:00 | Dinner | |
| October 26 Thursday | Day 4 | |
| 7:00-8:15 | Breakfast | |
| 8:30-11:00 | Session 5: Vaccines for prevention and therapy | |
| Chair: Ken Ishii | ||
| 8:30-8:55 | Lisa Butterfield | Cancer Vaccine Lessons |
| 8:55-9:20 | Mads Hald Andersen | Immune Modulatory Vaccines in Cancer Therapy |
| 9:20-9:45 | Ken Ishii | Science and design of nucleic acid-based vaccine and adjuvant |
| 9:45-10:10 | Lianpan Dai | Rational design of protective Zika vaccine to eliminate antibody-dependent enhancement of dengue infection |
| 10:10-10:35 | Enrico Lugli | Memory T cell responses in human cancer |
| 10:35-11:00 | Short Talks | |
| Wivine Burny | Innate IFN pathway predicts antibody quality persistence in adjuvanted vaccines | |
| Adriana Tomic | Warrior’s Tales: Targeting Memory T cells for Improved Influenza Vaccination Strategies | |
| 11:00-11:30 | Coffee break & Poster viewing | |
| 11:30-13:10 | Session 6: Tumor Immunotherapy | |
| Chair: Lisa Butterfield | ||
| 11:30-11:55 | Ana Anderson | Deciphering the rules governing reliance on TCF1 for immunotherapy response in cancer |
| 11:55-12:20 | Shicheng Su | Different routes, same destination, not same destiny-HEVs mold the immunogenicity of tumor escapees |
| 12:20-12:45 | Shuguang Tan | TCR recognition and immunotherapy by targeting KRAS mutation |
| 12:45-13:10 | Stephen Schoenberger | Specificity and regulation of neoantigen-specific T cells in cancer |
| 13:10 | Lunch | |
| 15:00-21:00 | Tour and dinner | |
| October 27 Friday | Day 5 | |
| 7:00-8:15 | Breakfast | |
| 8:30-11:00 | Session 7: Translating immunity: From Bedside to Bench and Back | |
| Chair: Peter Katsikis | ||
| 8:30-8:55 | Georg Schett | CAR T cell therapy in autoimmune disease |
| 8:55-9:20 | Aimee Payne | Learnings from the DesCAARTes phase 1 trial: precision cellular immunotherapies for autoimmunity |
| 9:20-9:45 | Steven Deeks | Immunotherapy and a Cure for HIV |
| 9:45-10:10 | Peter Katsikis | Bi-specific reagents for haematopoietic stem cell transplantation |
| 10:10-11:00 | Short Talks | |
| Yuan Chen | Inhibition of SUMOylation Induces Adaptive Anti-Tumor Immunity Against Pancreatic Cancer through Multiple Effects on the Tumor Microenvironment | |
| Peter Chockley | Novel KIR:HLA interactions enhance donor selection for hematopoietic cell transplantation and immunotherapy | |
| Burcu Temizoz | Immune resilience to cancer and viral infection by repurposing Mycobacterium tuberculosis-specific CD4+ memory T cells | |
| Sarah Edwards | An allogeneic Vδ1 γδ T cell enriched cell therapy for haematological cancer | |
| Ivan Odak | Prevention of antigen escape by modulation of off-target tumor killing in T cells | |
| 11:00-11:30 | Coffee break & Poster viewing | |
| 11:30-13:45 | Session 8: Immune system development and age | |
| Chair: Roxane Tussiwand | ||
| 11:30-11:55 | Donna Farber | Tissue and age determinants for resident immunity |
| 11:55-12:20 | Roxane Tussiwand | Understanding the prenatal Immune system |
| 12:20-12:45 | Muzlifah Haniffa | Decoding the Developing Human Immune System |
| 12:45-13:45 | Short Talks | |
| Andri Lemarquis | Recirculating regulatory T cells mediate thymic regeneration | |
| Julia Davis-Porada | Tissue-localized memory to COVID-19 vaccines | |
| Rebekka Duhen | Characterization of T cell subset in colorectal polyps, cancer and blood | |
| Maryam Eskandarian | Mesenchymal stem cells therapy changes the decidual microenvironment to modulate the dendritc cells properties in benefit of pregnancy maintenance | |
| Zoe Magill | Differential responses of mouse and human dendritic cells to clinical inhibitors used to treat melanoma | |
| 13:45 | Lunch | |
| 18:30-19:30 | Poster viewing | |
| 20:00 | Gala dinner | |
| October 28 Saturday | Day 6 | Departure |
| 7:00-9:30 | Breakfast |
