The program is organized in eight sessions that are chaired by speakers who are leaders in their respective fields. Each session includes talks by speakers that are 25 minute talk plus 5 minutes questions or 15min talk plus 5min questions, and short oral presentations that are 10 minute talk plus 2 minutes questions. Short oral presentations are selected from submitted abstracts. Posters are viewed for the duration of the conference.

To download the program schedule please click here

May 29 Wednesday Day 1 Arrival  
15:00-18:00   Registration  
19:00   Welcome Dinner  
May 30 Thursday Day 2    
7:00-8:15   Breakfast  
8:30-11:00   Session 1: Systems Immunology of Infections  
    Chair: Anne O’Garra  
8:30-9:00   Tom Ottenhoff, Leiden University Medical Center, The Netherlands Non-classical innate and adaptive immunity in host defence against Mycobacterium tuberculosis in humans 
9:00-9:30   Adrian Hayday, The Francis Crick Institute, UK Epithelial regulation and dysregulation of human adaptate T cells 
9:30-9:50   Shai Shen-Orr, Technion-Israel Institute of Technology, Israel Charting the Immunological Landscape – System Dynamics and Clinical Implications
9:50-10:10   Michelle Linterman, Babraham Institute, UK The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCR clonotypes
10:10-11:00   Jorge Domínguez-Andrés, Radboud UMC, The Netherlands The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity
    Simone Moorlag, Radboud UMC, The Netherlands BCG-vaccination induces innate memory in human neutrophils leading to nonspecific protection against reinfection
    Wivine Burny, GSK Vaccine, Belgium Transcriptomics analysis of early responses to HBs vaccines containing an Adjuvant System in humans
    Jayanti Mania-Pramanik, ICMR-National Institute for Research in Reproductive Health, India Contribution of host immunogenetic factors towards risk of HIV transmission: A study in Indian cohorts
11:00-11:30   Coffee break & Poster viewing   
11:30-13:45   Session 2: Discovering and Translating Human T cell Immunity  
    Chair: Peter Katsikis  
11:30-12:00   Rene van Lier, Sanquin, The Netherlands Leaving home: A role for TRM in Systemic Immunity?
12:00-12:30   Peter Katsikis, Erasmus University Medical Center, The Netherlands miRNA as regulators of CTL immunity
12:30-13:45   Sascha Rutz, Cancer Immunology, Genentech, South San Francisco, United States of America Gene editing in primary human T cells using CRISPR/Cas9
    Agnese Losurdo, Humanitas Research Hospital, Italy Defining T cell dysfunctionality in breast cancer by single cell analysis: implications for immunotherapy
    Manzhi Zhao, Erasmus University Medical Center, The Netherlands Establishment of an in vitro CD8 T cell exhaustion model
    Etienne Masle-Farquhar, Garvan Institute of Medical Research, Australia The effects of Germline STAT3-activating mutations from autoimmunity and lymphoid malignancy on mouse and human T cell development and function
    Lisanne Lutter, University Medical Centre Utrecht, The Netherlands Characterization of regulatory T cell programming and heterogeneity in an autoimmune inflammatory environment
    Emmanuelle Godefroy, CRCINA, INSERM U1232, France A novel gut-derived microbiota-specific circulating CD4+/CD8a+ human Treg subset: potential roles in homeostasis and diseases
13:45   Lunch  
18:30-19:30   Poster viewing & Drinks  
19:30   Dinner   
May 31 Friday Day 3    
7:00-8:15   Breakfast  
8:30-11:06   Session 3: Discovering and Translating Human T cell Immunity  
    Chair: Federica Sallusto  
8:30-9:20   Mark Davis, Stanford University, USA Tools for T cells: Specificity and function in autoimmunity, infectious diseases and cancer 
9:20-9:50   Federica Sallusto, Università della Svizzera Italiana, Switzerland Human Memory T Cell Subsets: From Phenotype To Function
9:50-10:10   Rama Amara Rao, Emory University, USA PD-1 Blockade Combined with Therapeutic Vaccination for Functional Cure Against HIV/AIDS
10:10-10:30   Amit Awasthi, Translational Health Science and Technology Institute, India EGFR-HIF1a signalling axis positively regulates the development of Th9 cells
10:30-11:06   Eloise Scamardella, Humanitas Research Hospital, Italy Interferon regulatory factor (IRF8) regulates memory formation by restraining FOXO1 expression
    Steven Koetzier, Erasmus University Medical Center, The Netherlands Deciphering glucocorticoid-resistant T helper cells driving multiple sclerosis disease activity
    Julia Bier,  Immunology, Garvan Institute, Sydney, Australia Activated PI3K Delta Syndrome: dissecting the effects of PI3K hyperactivation over T helper differentiation and function
11:06-11:30   Coffee break & Poster viewing   
11:30-13:45   Session 4: Understanding and Translating Human B cell responses  
    Chair: Rene Toes  
11:30-12:00   Antonio Lanzavecchia, Università della Svizzera Italiana, Switzerland Lessons from the analysis of the immune response to P. falciparum: the power of clonal selection
12:00-12:30   Xiao-Ning Xu, Imperial College London, UK Dissection of antibody responses to emerging infections in humans by yeast display
12:30-13:00   Rene Toes, Leiden University Medical Center, The Netherlands Take the bitter with the sweet; on the role of variable domain glycans and the breach of tolerance of auto-reactive B-cells in Rheumatoid Arthritis
13:00-13:20   Joshy Jacob, Emory University, USA Templated mutagenesis and the origin of B cell somatic mutants
13:20-13:45   Joanne H Reed, Garvan Institute of Medical Research, Australia Evolution of Pathogenic Autoantibody by Lymphoma Mutations in Rogue B Cell Clones
    Ian Setliff, Vanderbilt University Medical Center, USA High-throughput mapping of B-cell receptor sequence to antigen specificity
13:45   Lunch  
18:30-19:30   Poster viewing & Drinks  
19:30   Dinner   
June 1 Saturday Day 4    
7:00-8:15   Breakfast  
8:30-11:05   Session 5: Tumor Immunotherapy  
    Chair: Stephen Schoenberger  
8:30-9:00   Ugur Sahin, BioNTech Pharmaceuticals, Germany RNA-based vaccine approaches
9:00-9:30   Stephen Schoenberger, La Jolla Institute for Allergy & Immunology, USA Functional identification of tumor NeoAg
9:30-10:00   Özlem Türeci, Cluster for Individualized ImmunoIntervention (CI3), Germany Novel immunotherapies based on targeting Claudin family members
10:00-10:20   George Pavlakis, National Cancer Institute, USA Clinical development of heterodimeric IL-15 for cancer immunotherapy
10:20-10:40   Enrico Lugli, Humanitas Clinical and Research Center, Italy High-Dimensional Single-Cell Profiling Identifies an Effector Treg Molecular Program Governing Human Lung Cancer Disease Progression
10:40-11:05   Zhizhang Yang, Mayo Clinic, USA Mass cytometry defines loss of costimulatory receptor expression as a novel immune signature in follicular lymphoma
    Thomas Duhen, Providence Cancer Institute, USA A new strategy to identify and expand tumor-reactive CD8 TILs in human solid tumors
11:05-11:30   Coffee break & Poster viewing   
11:30-13:10   Session 6: Systems Immunology and Vaccines  
    Chair: Bali Pulendran  
11:30-12:00   Bali Pulendran, Stanford University, USA System-biological approaches to define immunological mechanisms of vaccine-induced immunity
12:00-12:30   Ken Ishii, University of Tokyo, Japan Nuclear cytokines and extracellular nucleic acids in infection and vaccination
12:30-12:50   Ioanna Skountzou, Emory University, USA TIV immunization with a thermostable microneedle patch-Immunogenicity and Transcriptomics results from a Phase I Clinical Trial
12:50-13:10   Petter Brodin, Karolinska Institute, Sweden Systems-level analysis of immune variation and the influence of environmental exposures early in life
13:10   Lunch  
17:30   Tour of Asklepeion  
19:30   Dinner Restaurant Oromedon  
June 2 Sunday Day 5    
7:00-8:15   Breakfast  
8:30-11:00   Session 7: Discovering and Translating Innate Immunity  
    Chair: Roxane Tussiwand  
8:30-9:00   Mihai Netea, Radboud University Medical Center, The Netherlands Metabolic and Epigenetic Reprogramming in trained Immunity
9:00-9:30   Anne O’Garra, The Francis Crick Institute, UK Cytokine interference in immunity to infection
9:30-10:00   Roxane Tussiwand, University of Basel, Switzerland & NIH, USA When origin matters: redefining the plasmacytoid dendritic cell subset
10:00-10:20   Eynav Klechevsky, Washington University in St. Louis, USA Upstream regulation of autoimmunity and cancer via human dendritic cell subsets
10:20-10:40   Evangelos Andreakos, Biomedical Research Foundation, Academy of Athens, Greece Lambda interferons constitute dual function cytokines mediating antiviral immunity and damage control
10:40-11:00   Dina Alexandropoulos, Icahn School of Medicine at Mount Sinai, USA Immune Profiling and Target Identification of Human Liver Inflammatory Diseases
11:00-11:30   Coffee break & Poster viewing   
11:30-13:50   Session 8: Translating immunity: From Bedside to Bench and Back  
    Chair: Helen Su  
11:30-12:20   Anahita Fathi, University Medical Center Hamburg-Eppendorf, Germany First-in-human clinical phase I trial of a novel virally vectored vaccine candidate against MERS-CoV
    Adriana Tomic, Stanford University, USA SIMON, an automated machine learning system reveals immune signatures of influenza vaccine responses
    Rosa Barreira da Silva, Genentech, USA Monocyte homeostasis is coordinated by N-terminal cyclization of CCR2 ligands
    Shyam Sushama Jose, St. Anne’s University Hospital, BRNO, Czech Republic Non-telomeric function of telomerase complex regulates pattern recognition receptors downstream signaling in tissue organoid models
12:20-12:50   Yong-Jun Liu, Sanofi, France Translating human immunobiology to medicine
12:50-13:20   Helen Su, National Institutes of Health (NIH), USA Mechanistic insights into human immunity through the study of a novel human immunodeficiency-immunodysregulation disorder
13:20-13:50   Rino Rappuoli, GSK Vaccines, Italy Antimicrobial resistance, a threat for our planet as big as climate change, and the role of vaccines
13:50   Lunch  
20:00   Gala dinner  
June 3 Monday Day 6 Departure  
7:00-9:30   Breakfast